Jun 25, · Pleurisy is inflammation of the lining of your chest, outside of your lungs. If the right lung is affected, then you’ll feel pain on the right side of your breast. Other symptoms include Author: Scott Frothingham. Most people with pleurisy experience sharp or stabbing chest pain, also known as pleuritic pain. This pain often worsens when you cough or breathe in deeply. Sometimes the pain can spread to the shoulder or back.